农业基因组学

A pangenome is a collection of genomes from a population of species that represents the genetic diversity of the population. Pangenomes typically are 20-30 genomes depending on the biodiversity of the population. Pangenomes obtained through HiFi sequencing can be resolved into haplotype databases for enhanced trait imputation for desirable phenotypes for breeding.

Whole genome sequencing, transcriptome sequencing, epigenomics, metagenomics, and the targeted sequencing of plants, animals, fungi, bacteria, and complex populations can all be leveraged for your agricultural research in different areas. This includes breeding, pest management, and genome engineering.

Genome engineering, or gene editing, is a process where scientists can change the genetic information of agriculturally important species with biomolecular tools such as CRISPR-Cas9. HiFi sequencing can help you validate where edits are made on a genome-wide or targeted basis. It can also help you design more efficient workflows with extremely accurate genomic information.

HiFi sequencing enables agriscientists to generate haplotype-resolved, high-quality genomes that span most variant types. Complex traits, such as drought resistance and pest resistance, can be explained by a combination of genes, structural variants, copy number variants, and more. Agriscientists can harness this genetic information to inform marker development.