Application brief — Germline variant detection with the Onso system
Powered by sequencing by binding (SBB) chemistry, the PacBio short- read Onso platform delivers extraordinary base-calling accuracy (90% of bases at ≥Q40), setting a new standard in genetic research. This remarkable accuracy instills a new level of confidence in sequencing data and improves the ability to characterize challenging genetic variations through genome- wide and targeted approaches.