PacBio Literature

The Revio™ system empowers HiFi sequencing. It adds affordability, high throughput, and ease of use to a foundation of long reads, exceptional accuracy, and direct methylation detection.

Vega system specification sheet

See it all with HiFi sequencing on the Revio™ system

Vega benchtop system brochure

HiFi systems brochure

Highlighting publications using Iso-Seq in cancer research to demonstrate how bulk and single-cell Iso- Seq data detects fusion genes, identifies novel isoforms that might serve as neoepitopes for vaccine candidates, and traces clonal evolution.

This technical note describes the experimental conditions of a modified workflow preparing PacBio Kinnex single-cell libraries with Twist exome enrichment kits.

Reveal the complexity of the human genome to power human disease research — With the advancement of highly accurate long-read sequencing, missing pieces could be resolved and fully complete the genome. PacBio HiFi sequencing gave rise to this achievement and has dramatically improved understanding of the human genome by resolving gaps that are unattainable by other sequencing methods, accurately mapping complex regions, and enabling more contiguous genome assemblies.

Sequencing has become an integral part of the biopharma research and development process and enhances our understanding of the molecular determinants of health and disease. Whether you are conducting research on novel potential drug targets, biomarkers, or therapeutics such as gene therapies, PacBio® offers highly accurate sequencing solutions across its portfolio that can improve your chances of success and may reduce your time to market.

This technical note describes the procedure for targeted enrichment using IDT xGen Hyb and Wash kit v3 for Kinnex™ full-length RNA libraries.

Unravel the complexity of plant and animal biology for any species with HiFi sequencing. Discover more about species and populations with more accurate genomes, transcriptomes, and epigenomes.

PacBio® HiFi sequencing enables greater variant detection in more regions of the genome than alternative technologies, providing exceptional insight at any depth. Choosing the right level of sequencing coverage is a critical first step for project planning

Highly accurate long reads – HiFi reads – with single-molecule resolution make Single Molecule, Real-Time (SMRT) Sequencing ideal for full-length 16S rRNA sequencing, shotgun metagenomic profiling, and metagenome assembly.

With Single Molecule, Real-Time (SMRT) Sequencing and the Sequel Systems, you can affordably assemble reference-quality microbial genomes that are >99.999% (Q50) accurate.

Detect, track, and characterize pathogens to a new standard of completeness and precision. PacBio® solutions offer unmatched accuracy and long read lengths to support a wide range of pathogen surveillance applications.