2024年03月21日 | 靶向测序
Asset Type： Application and Product Notes
2023年11月15日 | RNA测序
Application note – Robust detection of somatic variants from tumor-normal samples with highly accurate long-read whole genome sequencing
2023年11月01日 | RNA测序
Application note — Kinnex single-cell RNA kit for single cell isoform sequencing
2023年10月19日 | procedures + protocols 产品、程序+实验方案
Application note — Consolidated analysis tools with the PacBio WGS Variant Pipeline
2023年09月19日 | RNA测序
Application note — Full-length HiFi sequencing of eukaryotic ITS and rRNA amplicons
2023年05月17日 | 表观遗传学
Application brief — BugSeq taxonomic and functional profiling with HiFi metagenomics
2023年03月14日 | 靶向测序
Application note HiFi targeted sequencing and comprehensive analysis of SMN1 2 with Paraphase
2022年10月20日 | 人类遗传学研究
Application note – HiFi amplicon sequencing for congenital adrenal hyperplasia
In this Application Note, we focus on HiFi sequencing of full-length PCR amplicons spanning the 3.3 kb CYP21A2 and its pseudogene, CYP21A1P. PacBio HiFi reads are long (up to 25 kb) and accurate (99.9%) making them well suited to analyze the complexity of CAH-related pathogenic variants, where gene conversions and chimeric genes are the predominant mutation types.
2022年10月20日 | 靶向测序
Application note – HiFi amplicon sequencing for Thalassemia
PacBio® HiFi reads are long (up to 25 kb) and accurate (99.9%). Targeted HiFi sequencing of amplicons has the ability to span entire genes, allowing for straightforward haplotype construction, detection of structural variants or copy number variants in addition to SNVs and indels. These attributes make targeted HiFi sequencing well suited to analyze both rare and common variants of all types, thus increasing the positive detection rate of thalassemia-related variants.
2022年10月07日 |
Application note HiFi amplicon sequencing for pharmacogenetics CYP2D6
With PacBio® HiFi sequencing, CYP2D6 variation can be captured using highly accurate long reads on a single platform. Amplicon-based HiFi sequencing fully and directly resolves and phases complex loci like CYP2D6 without assembly or inference, allowing for ancestry agnostic haplotype assignment.
2022年07月05日 | 传染病研究
HiFiViral SARS-CoV-2 Kit enables genomic surveillance of COVID-19
The HiFiViral SARS-CoV-2 kit is an end-to-end solution
for genomic surveillance of COVID-19 variants. The kit
utilizes molecular inversion probes (MIPs), a
differentiated enrichment technology which combines
the simplicity and cost-effectiveness of PCR with the
resilience to mutations of target capture. The MIPs
approach, coupled with PacBio HiFi reads and SMRT®
Link software analysis, delivers several advantages
over PCR amplicon sequencing
