One single technology. The whole multi-omic view.
PacBio HiFi reads on our Revio and Vega systems are both long (up to 25 kb) and accurate (≥90% of bases at Q30+), while including direct detection of epigenetic modifications like methylation. This means that researchers can take a wholistic and multi-omic approach to understanding cancer biology with a single technology that can access complete cancer genomes, epigenomes, and transcriptomes.
肿瘤研究解决方案
为了实现肿瘤精准医疗的承诺,需要更好地了解肿瘤的复杂生物学。PacBio 高度准确的长读长测序让您能够以卓越的精度发现新的RNA异构体、融基因和结构变异。
Reveal hidden biomarkers
PacBio technology allows cancer researchers to access the full spectrum of variation to find new biomarkers associated with tumor growth, progression, and resistance. Existing short read methods lack the read length to characterize structural variants or span larger repetitive regions, or to phase variants into haplotypes to identify whether mutations are in cis or in trans. At the same time, other long reads lack the accuracy to precisely pinpoint fusion breakpoints or to accurately call smaller variants like SNVs and indels. With PacBio sequencing, researchers can address any question, any variant type, and any application in cancer genomics.

手册
PacBio 的高精度长短读测序技术可全面描述导致癌症的变化,并有助于发现新一代癌症生物标记物。
PacBio 提供的高精度长短线程测序技术使癌症研究人员能够在一次检测中确定癌症变异的全部特征,从而更清晰地了解癌症的生物学特性,帮助确定新的治疗靶点并为临床决策提供依据。
肿瘤研究实践